Leptospirosis Detection

Using Artificial Intelligence to Predict Life-Threatening Bacterial Disease in Dogs

UC Davis Veterinarians Develop AI Model for Accurate, Early Detection of Leptospirosis Infections

Written by Rob Warren

Leptospirosis, a disease that dogs can get from drinking water contaminated with Leptospira bacteria, can cause kidney failure, liver disease and severe bleeding into the lungs. Early detection of the disease is crucial and may mean the difference between life and death.

Veterinarians and researchers at the University of California, Davis, School of Veterinary Medicine have discovered a technique to predict leptospirosis in dogs through the use of artificial intelligence. After many months of testing various models, the team has developed one that outperformed traditional testing methods and provided accurate early detection of the disease. The groundbreaking discovery was published in Journal of Veterinary Diagnostic Investigation and it made in to the news -- watch here.

“Traditional testing for Leptospira lacks sensitivity early in the disease process,” said lead author Krystle Reagan, a board-certified internal medicine specialist and assistant professor focusing on infectious diseases. “Detection also can take more than two weeks because of the need to demonstrate a rise in the level of antibodies in a blood sample. Our AI model eliminates those two roadblocks to a swift and accurate diagnosis.”

The research involved historical data of patients at the UC Davis Veterinary Medical Teaching Hospital that had been tested for leptospirosis. Routinely collected blood work from these 413 dogs was used to train an AI prediction model. Over the next year, the hospital treated an additional 53 dogs with suspected leptospirosis. The model correctly identified all nine dogs that were positive for leptospirosis (100% sensitivity). The model also correctly identified approximately 90% of the 44 dogs that were ultimately leptospirosis negative.

The goal for the model is for it to become an online resource for veterinarians to enter patient data and receive a timely prediction.

This research was done in collaboration with members of UC Davis’ Center for Data Science and Artificial Intelligence Research, led by professor of mathematics Thomas Strohmer. He and his students were involved in the algorithm building.

Read the entire article at UC Davis News.

This research also made it to the news. Check this out!